Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CTSG | P08311 | 2/20 | 0.37 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28481670 | 0.83 | TRPA1 (0.41) | TRPA1ATMALDH1A1CTSGCMA1 | |
| SCHEMBL8404359 | 0.80 | CTSG (0.37) | TRPA1ATMALDH1A1CTSGCMA1 | |
| SCHEMBL6327715 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CTSGCMA1CYP2D6CYP2C19 | |
| SCHEMBL28388316 | 0.75 | SMN1; SMN2 (0.36) | ALDH1A1HSD17B1HSD17B2MAPTKDM4E | |
| SCHEMBL4298612 | 0.75 | CTSG (0.37) | ALDH1A1CTSGCMA1PTGS1PTGS2 | |
| SCHEMBL23980164 | 0.75 | ACHE (0.39) | ALDH1A1CTSGCMA1MAPTCYP1A2 | |
| SCHEMBL17140136 | 0.75 | CTSG (0.35) | ALDH1A1CTSGCMA1MAPTCYP1A2 | |
| SCHEMBL2314303 | 0.75 | CYP2A6 (0.53) | ALDH1A1CTSGCMA1CYP2D6CYP2C19 | |
| SCHEMBL4429297 | 0.74 | MAPT (0.34) | ALDH1A1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL4295213 | 0.73 | KDM4E (0.47) | TRPA1ALDH1A1CTSGCMA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362854-B1 | Benzo[b[thiophene derivatives and process for producing the same | TEIJIN PHARMA LTD (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-1792614-A1 | Benzo[b]thiophene derivatives | Teijin Pharma Limited (JP) | 2007-06-06 | — | — | EP | disclosed |
| US-6884896-B2 | Benzo[b]thiophene derivatives and process for preparing the same | TEIJIN LIMITED (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1362854-A1 | BENZO b]THIOPHENE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-20030176490-A1 | Benzo(b)thiophene derivatives and process for producing the same | TEIJIN PHARMA LIMITED (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176490-A1 | Benzo(b)thiophene derivatives and process for producing the same | CYP4B1, CYP1B1, CYP3A4 | TRPA1 1923/4885ATM 2946/4885ALDH1A1 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.