Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 3/20 | 0.37 |
| ▸ | CMA1 | P23946 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092548 | 0.83 | CYP2A6 (0.41) | CYP2A6TSHRMAPTALDH1A1CYP1A2 | |
| SCHEMBL8404359 | 0.80 | CTSG (0.37) | CTSGCMA1CYP2A6TSHRACHE | |
| SCHEMBL3150930 | 0.80 | LMNA (0.41) | CYP2A6TSHRMAPTDYRK3MAP4K4 | |
| SCHEMBL6327715 | 0.77 | ALDH1A1 (0.41) | CTSGCMA1CYP2A6TSHRACHE | |
| SCHEMBL23980164 | 0.75 | ACHE (0.39) | CTSGCMA1CYP2A6TSHRACHE | |
| SCHEMBL20787934 | 0.75 | CTSG (0.35) | CTSGCMA1CYP2A6TSHRACHE | |
| SCHEMBL5178307 | 0.75 | TRPA1 (0.41) | CTSGCMA1CYP2A6MAPTSMN1; SMN2 | |
| SCHEMBL17140136 | 0.75 | CTSG (0.35) | CTSGCMA1CYP2A6TSHRACHE | |
| SCHEMBL13888151 | 0.72 | CTSG (0.47) | CTSGCMA1CYP2A6SMN1; SMN2ALDH1A1 | |
| SCHEMBL10692123 | 0.71 | CYP2A6 (0.36) | CYP2A6MAPTDYRK3MAP4K4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264663-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJEN PHARMA LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20090264663-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJEN PHARMA LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1947096-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVE AND METHOD FOR PRODUCING SAME | Teijin Pharma Limited (JP) | 2008-07-23 | — | — | EP | disclosed |
| EP-1947096-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVE AND METHOD FOR PRODUCING SAME | Teijin Pharma Limited (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-4737516-A | FUNGICIDES | SANDOZ LTD. (CH) | 1988-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264663-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | CMA1, TPSB2, TPSAB1 | CTSG 196/4885CMA1 1/4885CYP2A6 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.