Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 3/20 | 0.42 |
| ▸ | CMA1 | P23946 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130704 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL4298267 | 0.79 | TSHR (0.50) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL6130745 | 0.79 | TSHR (0.44) | KDM4EALDH1A1HSD17B10KMT2ACYP1A2 | |
| SCHEMBL14886651 | 0.79 | ALB (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL5351904 | 0.75 | TAS2R14 (0.41) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL8404359 | 0.74 | CTSG (0.37) | ALDH1A1CTSGCMA1TRPA1CYP1A2 | |
| SCHEMBL5178307 | 0.73 | TRPA1 (0.41) | KDM4EALDH1A1HPGDHSD17B10CTSG | |
| SCHEMBL31721926 | 0.72 | ALB (0.41) | KDM4EALDH1A1HSD17B10MYCKMT2A | |
| SCHEMBL6327715 | 0.71 | ALDH1A1 (0.41) | ALDH1A1CTSGCMA1CYP1A2TSHR | |
| SCHEMBL13888151 | 0.70 | CTSG (0.47) | ALDH1A1CTSGCMA1CYP1A2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264663-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJEN PHARMA LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20090264663-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJEN PHARMA LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20090264663-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | TEIJEN PHARMA LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1947096-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVE AND METHOD FOR PRODUCING SAME | Teijin Pharma Limited (JP) | 2008-07-23 | — | — | EP | disclosed |
| EP-1947096-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVE AND METHOD FOR PRODUCING SAME | Teijin Pharma Limited (JP) | 2008-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264663-A1 | 3-HYDROXYMETHYLBENZO[b]THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | CMA1, TPSB2, TPSAB1 | KDM4E 205/4885ALDH1A1 1138/4885HPGD 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.