1,6-Hexanediol

1,6-Hexanediol

SCHEMBL517945

CC(C)(C)c1cc(C(C)(C(=O)O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O.OCCCCCCO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 4/20 0.45
GSR P00390 2/20 0.44
GLRA3 O75311 1/20 0.43
GLRB P48167 1/20 0.43
GABBR2 O75899 2/20 0.43
GABBR1 Q9UBS5 2/20 0.43
CA2 P00918 2/20 0.41
CA1 P00915 1/20 0.41
ALDH1A1 P00352 5/20 0.41
LMNA P02545 3/20 0.41
HPGD P15428 2/20 0.41
MAPK1 P28482 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
RECQL P46063 1/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
POLB P06746 2/20 0.40
GAA P10253 2/20 0.40
TSHR P16473 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL7080497 0.92 GSR (0.47) VCAM1GSRGLRA3GLRBGABBR2
1,6-Hexanediol SCHEMBL26092101 0.91 NR5A2 (0.44) VCAM1GSRGLRA3GLRBGABBR2
SCHEMBL2860842 0.88 GLRA3 (0.53) GLRA3GLRBGABBR2GABBR1CA2
SCHEMBL2765770 0.86 GLRA3 (0.42) VCAM1GLRA3GLRBGABBR2GABBR1
SCHEMBL29045735 0.85 ALDH1A1 (0.45) VCAM1GSRGLRA3GLRBGABBR2
Di(Hydroxyethyl)Ether SCHEMBL3683440 0.84 GSR (0.42) VCAM1GSRGLRA3GLRBGABBR2
1,6-Hexanediol SCHEMBL11706482 0.81 VCAM1 (0.43) VCAM1GSRGLRA3GLRBGABBR2
SCHEMBL517943 0.81 VCAM1 (0.43) VCAM1GSRGABBR2GABBR1CA2
SCHEMBL28556532 0.80 LMNA (0.41) GSRGLRA3GLRBGABBR2GABBR1
1,6-Hexanediol SCHEMBL10591614 0.80 LMNA (0.50) VCAM1GSRGLRA3GLRBGABBR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2878630-B1 Polyamide compositions LANXESS DEUTSCHLAND GMBH (DE) 2019-11-20 EP claimed
US-20190292366-A1 POLYAMIDE COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2019-09-26 US claimed
EP-1846367-B1 ALIPHATIC, CYCLOALIPHATIC OR (CYCLO)ALIPHATIC DIISOCYANATES THAT ARE STABLE IN STORAGE EVONIK DEGUSSA GMBH (DE) 2016-03-09 EP claimed
US-20100168329-A1 ALIPHATIC, CYCLOALIPHATIC OR (CYCLO)ALIPHATIC DIISOCYANATES THAT ARE STABLE IN STORAGE DEGUSSA GMBH (DE) 2010-07-01 US claimed
US-6339132-B1 COMPRESSING IN COMPRESSOR UNREACTED VINYL CHLORIDE MONOMER RECOVERED FROM A PROCESS OF VINYL CHLORIDE POLYMER OR COPOLYMER PRODUCTION, IN CONTACT WITH LUBRICATING OIL FED INTO COMPRESSOR; DISCHARGING MIXTURE; SEPARTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-01-15 US claimed
US-20260103596-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-1 BASF SE (DE) 2026-04-16 US disclosed
US-20260103594-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-3 BASF SE (DE) 2026-04-16 US disclosed
EP-4536741-B1 RECYCLING METHOD FOR PRODUCING A POLYAMIDE COMPOUND BASF SE (DE) 2026-01-21 EP disclosed
US-20250320346-A1 RECYCLING METHOD FOR PRODUCING A POLYAMIDE COMPOUND BASF SE (DE) 2025-10-16 US disclosed
WO-2025049564-A1 POLYAMIDE MOLDING COMPOSITIONS WITH IMPROVED HEAT-AGING RESISTANCE BASF SE (DE) 2025-03-06 WO disclosed
EP-4255964-B1 AQUEOUS LACTAM SOLUTION OF LIGNIN BASF SE (DE) 2024-11-13 EP disclosed
US-20240279464-A1 THERMOPLASTIC MOULDING COMPOSITION RETAINING HIGH GLOSS BASF SE (DE) 2024-08-22 US disclosed
US-20010034415-A1 Impact-modified thermoplastic polymer mixtures based on SO2 copolymers having an aliphatic main chain BASF AKTIENGESELLSCHAFT (DE) 2001-10-25 US disclosed
EP-1043313-A1 NEW ACRYLATES AND ACTINIC RADIATION-CURABLE COMPOSITIONS CONTAINING THEM Toagosei Co., Ltd. (JP) 2000-10-11 EP disclosed
US-5808138-A BUBBLING OR ADDING SOLID CARBON DIOXIDE BASF AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
US-5728317-A POLYISOCYANURATES FROM POLYISOCYANATES WITH STABILIZERS BASF AKTIENGESELLSCHAFT (DE) 1998-03-17 US disclosed
EP-0643042-B1 Storage-stable polyisocyanate mixtures prepared by phosgen-free processes, a process for their preparation and their use BASF AG (DE) 1996-07-17 EP disclosed
EP-0645372-A1 Stable polyisocyanate mixtures prepared by phosgen-free processes and a process for their preparation BASF Aktiengesellschaft (DE) 1995-03-29 EP disclosed
EP-0643042-A1 Storage-stable polyisocyanate mixtures prepared by phosgen-free processes, a process for their preparation and their use BASF Aktiengesellschaft (DE) 1995-03-15 EP disclosed
EP-0513619-A2 Compositions suited as stabilizersystems for polymers BAYER AG (DE) 1992-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103594-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-3 SMC3, ASIC3, PUF60 VCAM1 1911/4885GSR 3485/4885GLRA3 2807/4885
US-20100168329-A1 ALIPHATIC, CYCLOALIPHATIC OR (CYCLO)ALIPHATIC DIISOCYANATES THAT ARE STABLE IN STORAGE DDT, AADAC, SCD VCAM1 3917/4885GSR 3072/4885GLRA3 1170/4885
US-20260103596-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-1 PUF60, PHPT1, P4HA1 VCAM1 3353/4885GSR 4522/4885GLRA3 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.