Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRF | P10586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431628 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPK1HSD17B10HPGDCYP2A6 | |
| SCHEMBL5584043 | 0.83 | LMNA (0.31) | ALDH1A1MAPK1 | |
| SCHEMBL11746658 | 0.81 | CYP1A2 (0.38) | ALDH1A1HSD17B10CYP2A6CASP3SENP8 | |
| SCHEMBL9567440 | 0.81 | ALDH1A1 (0.31) | ALDH1A1MAPK1 | |
| SCHEMBL9321438 | 0.81 | PTGS2 (0.38) | ALDH1A1MAPK1HPGDPTGS2L3MBTL1 | |
| SCHEMBL7818368 | 0.81 | RAB9A (0.38) | ALDH1A1MAPK1HPGDTDP1TP53 | |
| SCHEMBL5745205 | 0.79 | MAOB (0.37) | ALDH1A1MAPK1HSD17B10HPGDTP53 | |
| SCHEMBL185890 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPK1HSD17B10HPGDBCL2L1 | |
| SCHEMBL457363 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPK1HSD17B10HPGDTDP1 | |
| SCHEMBL11512521 | 0.77 | MAP4K4 (0.46) | ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797083-A1 | SULFONAMIDE COMPOUNDS | Janssen Pharmaceutica, N.V. (BE) | 2007-06-20 | — | — | EP | claimed |
| WO-2006036670-A1 | SULFONAMIDE COMPOUNDS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-04-06 | — | — | WO | claimed |
| US-4060623-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | claimed |
| US-4038404-A | 1,2,4-TRIAZOLE ANTIMYCOTIC COMPOSITIONS AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | claimed |
| US-4036966-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | claimed |
| US-4036967-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | claimed |
| US-5358966-A | Using n,n'-diacylhydrazine | ROHM AND HAAS COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| US-4623583-A | Flame retardant textile fabrics | WHITE CHEMICAL CORPORATION (US) | 1986-11-18 | — | — | US | disclosed |
| US-4348306-A | Flame retardants | WHITE CHEMICAL CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| US-4267117-A | INTERMEDIATES FOR 1A-HYDROXYLATED CALCIFEROLS | THE UPJOHN COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| US-4206131-A | 1A-HYDROXYLATED CALCIFEROLS | THE UPJOHN COMPANY (US) | 1980-06-03 | — | — | US | disclosed |
| US-4158077-A | ORGANIC BROMINATED COMPOUND | WHITE CHEMICAL CORPORATION (US) | 1979-06-12 | — | — | US | disclosed |
| US-4120798-A | ORGANIC BROMINATED COMPOUND OF VERY SMALL SIZE, AQUEOUS SUSPENDING MEDIUM, PROTECTIVE COLLOID | WHITE CHEMICAL CORPORATION (US) | 1978-10-17 | — | — | US | disclosed |
| US-4060623-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |
| US-4038406-A | 1,2,4-TRIAZOLE ANTIMYCOTIC COMPOSITIONS AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
| US-4038404-A | 1,2,4-TRIAZOLE ANTIMYCOTIC COMPOSITIONS AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
| US-4036967-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-4036966-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
| US-4002763-A | 1,2,4-Triazole antimycotic compositions and use thereof | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | disclosed |
| US-3974310-A | Flame retardants for synthetic materials (I) | WHITE CHEMICAL CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |