SCHEMBL518447

SCHEMBL518447

CCCCN(C(=O)c1ccc(C2OCC3(CO2)COC(c2ccc(C(=O)N(CCCC)C4CCCCC4)cc2)OC3)cc1)C1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 5/20 0.46
AGER Q15109 3/20 0.39
MTNR1A P48039 1/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
SLC6A9 P48067 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10721820 0.84 HSD11B1 (0.57) HSD11B1AGERMTNR1ATHRATHRB
SCHEMBL517308 0.80 LMNA (0.54) HSD11B1NPC1RAB9ASMN1; SMN2
SCHEMBL9001746 0.78 HSD11B1 (0.54) HSD11B1AGERMTNR1ATHRB
SCHEMBL517387 0.76 ALDH1A1 (0.55) NPC1RAB9ASMN1; SMN2
SCHEMBL10722512 0.76 HSD11B1 (0.56) HSD11B1AGERMTNR1ATHRATHRB
SCHEMBL10722289 0.74 HSD11B1 (0.56) HSD11B1AGERMTNR1ATHRBSLC6A9
SCHEMBL27811000 0.74 AGER (0.52) HSD11B1AGERMTNR1ATHRATHRB
SCHEMBL9543490 0.74 MEN1 (0.51) HSD11B1AGERMTNR1ATHRATHRB
SCHEMBL4557404 0.73 AGER (0.50) HSD11B1AGERMTNR1A
SCHEMBL10724404 0.72 TRPM8 (0.55) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392458-B1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEM CO LTD (JP) 2018-03-14 EP disclosed
US-9023921-B2 Method for inhibiting crystal growth rate of amide compound and method for producing molded article of polyolefin-based resin NEW JAPAN CHEMICAL CO., LTD. (JP) 2015-05-05 US disclosed
EP-2431415-A1 METHOD FOR CONTROLLING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN New Japan Chemical Co., Ltd. (JP) 2012-03-21 EP disclosed
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-09 US disclosed
US-20120028006-A1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
EP-2392458-A2 POLYPROPYLENE RESIN MOLDED ARTICLE New Japan Chemical Co., Ltd. (JP) 2011-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN MNAT1, RFT1, RTF1 HSD11B1 2307/4885AGER 3937/4885MTNR1A 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.