SCHEMBL51857

SCHEMBL51857

CC(C)c1ccc(C(c2ccccc2)c2ccc(C(C)C)cc2O)c(O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 4/20 0.51
TRPA1 O75762 2/20 0.50
PTGS1 P23219 1/20 0.50
CACNA1C Q13936 1/20 0.50
ALOX12 P18054 3/20 0.46
ALDH1A1 P00352 3/20 0.46
HTT P42858 2/20 0.46
TP53 P04637 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MDM4 O15151 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
CA5A P35218 1/20 0.46
HDAC4 P56524 1/20 0.46
MDM2 Q00987 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51407 0.85 ALOX12 (0.48) TYRTRPA1PTGS1CACNA1CALOX12
SCHEMBL771497 0.80 LMNA (0.61) TYRTRPA1PTGS1CACNA1CALOX12
SCHEMBL11833120 0.80 TYR (0.46) TYRTRPA1PTGS1CACNA1CALOX12
SCHEMBL1345558 0.80 RNASEH1 (0.45) TYRTRPA1PTGS1CACNA1CALOX12
SCHEMBL1345503 0.80 RNASEH1 (0.45) TYRTRPA1PTGS1CACNA1CALOX12
SCHEMBL1343861 0.80 RNASEH1 (0.45) TYRTRPA1PTGS1CACNA1CALOX12
SCHEMBL1345540 0.80 RNASEH1 (0.45) TYRTRPA1PTGS1CACNA1CALOX12
SCHEMBL50970 0.79 TRPA1 (0.57) TYRTRPA1PTGS1CACNA1CALDH1A1
SCHEMBL19806857 0.79 TYR (0.53) TYRTRPA1PTGS1CACNA1CALOX12
SCHEMBL84243 0.79 TYR (0.67) TYRALDH1A1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8129307-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-03-06 US disclosed
US-20110269622-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-11-03 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
EP-2112001-B1 THERMOSENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2011-05-11 EP disclosed
EP-2261045-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2010-12-15 EP disclosed
EP-2181853-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2010-05-05 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
EP-1437231-B1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API CORP (JP) 2008-01-09 EP disclosed
US-20040241598-A1 Developer for thermal recording material and thermal recording materials NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-12-02 US disclosed
EP-1437231-A1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API Corporation (JP) 2004-07-14 EP disclosed