Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.69 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.69 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915870 | 0.86 | CHKA (0.65) | L3MBTL3L3MBTL1TDP1MAPTNPSR1 | |
| SCHEMBL23682966 | 0.84 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1MBTD1TP53BP1MAPT | |
| SCHEMBL23682830 | 0.84 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1MBTD1TP53BP1MAPT | |
| SCHEMBL23682686 | 0.84 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1MBTD1TP53BP1MAPT | |
| SCHEMBL23682854 | 0.82 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1MBTD1TP53BP1MAPT | |
| SCHEMBL13959204 | 0.81 | HTR1A (0.71) | L3MBTL3L3MBTL1HRH3MBTD1SIGMAR1 | |
| SCHEMBL23682667 | 0.81 | L3MBTL3 (1.00) | L3MBTL3L3MBTL1MBTD1TP53BP1MAPT | |
| SCHEMBL13959546 | 0.80 | L3MBTL1 (0.96) | L3MBTL3L3MBTL1HRH3MBTD1SIGMAR1 | |
| SCHEMBL13958981 | 0.80 | L3MBTL1 (0.96) | L3MBTL3L3MBTL1HRH3MBTD1SIGMAR1 | |
| SCHEMBL13958507 | 0.80 | L3MBTL1 (0.96) | L3MBTL3L3MBTL1HRH3MBTD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868605-A2 | PHENYL AND PYRIDYL LTA4H MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006105304-A2 | PHENYL AND PYRIDYL LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | WO | disclosed |
| US-20060223792-A1 | Phenyl and pyridyl LTA4H modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223792-A1 | Phenyl and pyridyl LTA4H modulators | LTA4H, LTB4R, LTC4S | L3MBTL3 2373/4885L3MBTL1 1749/4885HRH3 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.