Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214027 | 0.74 | NPC1 (0.53) | HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL5191103 | 0.73 | RAB9A (0.51) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5193058 | 0.73 | KMT2A (0.45) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5195066 | 0.72 | KMT2A (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL5193739 | 0.71 | PKM (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5193835 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2NOS2 | |
| SCHEMBL5193913 | 0.71 | NPC1 (0.44) | HPGDMEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL5191591 | 0.71 | TP53 (0.53) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25118371 | 0.70 | BCHE (0.43) | — | |
| SCHEMBL14679161 | 0.70 | HPGD (0.59) | HPGDMEN1KMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |