SCHEMBL5192085

SCHEMBL5192085

C1=CC2CCC1C2.C=C(C(=O)OC(C)(C)C)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196496 0.81 DGAT1 (0.33)
SCHEMBL4371659 0.76
SCHEMBL5403833 0.74 CHRM2 (0.37) CHRM2CHRM1CHRM3
SCHEMBL15365687 0.72 CHRM2 (0.33) CHRM2CHRM1CHRM3
SCHEMBL6065300 0.69 HRH3 (0.37) CHRM2CHRM1CHRM3
SCHEMBL6105532 0.69 CYP17A1 (0.37)
SCHEMBL6105744 0.69 EPHX2 (0.31)
SCHEMBL2367896 0.69 DGAT1 (0.30)
SCHEMBL5944187 0.68
SCHEMBL14557142 0.68 PDK1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070264587-A1 Resist Composition DOW CORNING CORPORATION 2007-11-15 US disclosed
EP-1810084-A1 RESIST COMPOSITION Dow Corning Corporation (US) 2007-07-25 EP disclosed
WO-2006049720-A1 RESIST COMPOSITION DOW CORNING CORPORATION (US) 2006-05-11 WO disclosed