Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5196161 | 0.85 | RAB9A (0.46) | RARARARBRARGALOX5KDM4E | |
| SCHEMBL5194112 | 0.84 | SMN1; SMN2 (0.51) | USP2RARARARBRARGALOX5 | |
| SCHEMBL3816963 | 0.76 | USP2 (0.41) | USP2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5196165 | 0.75 | MAPT (0.45) | ALOX5KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3807725 | 0.72 | HSD17B1 (0.43) | KDM4EMAPTRAB9ANPC1 | |
| SCHEMBL13685249 | 0.71 | SMN1; SMN2 (0.61) | ALOX5KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5196153 | 0.71 | SMN1; SMN2 (0.55) | RARARARBRARGALOX5KDM4E | |
| SCHEMBL3815731 | 0.68 | HDAC6 (0.39) | ALDH1A1SMN1; SMN2MAPTRAB9AMLYCD | |
| SCHEMBL5193555 | 0.68 | KMT2A (0.55) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5197734 | 0.68 | POLB (0.49) | ALOX5KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321463-B1 | Thiazole derivatives and their use for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC (CA) | 2007-08-08 | — | — | EP | claimed |