Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594988 | 0.77 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL5194246 | 0.77 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL5010288 | 0.74 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL5011001 | 0.73 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL2340883 | 0.72 | MCL1 (0.33) | CTSSCTSK | |
| SCHEMBL17275350 | 0.71 | MCL1 (0.32) | CTSSCTSK | |
| SCHEMBL5195724 | 0.68 | CTSS (0.32) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6403625 | 0.66 | CA2 (0.33) | CTSSCTSK | |
| SCHEMBL6410182 | 0.66 | CA2 (0.33) | CTSSCTSK | |
| SCHEMBL7442178 | 0.64 | DGAT1 (0.42) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812383-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | Smithkline Beecham Corporation (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006052722-A1 | GLYCOGEN PHOSPHORYLASE INHIBITOR COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 2006-05-18 | — | — | WO | disclosed |