Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.33 |
| ▸ | FEN1 | P39748 | 5/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199399 | 0.88 | DGAT1 (0.38) | DGAT1ALOX5APFEN1 | |
| SCHEMBL5199755 | 0.84 | GABRA2 (0.39) | DGAT1 | |
| SCHEMBL5199515 | 0.81 | TGFBR1 (0.34) | DGAT1FFAR4 | |
| SCHEMBL5199994 | 0.69 | TGFBR1 (0.36) | DGAT1ALOX5APFEN1 | |
| SCHEMBL5197940 | 0.68 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL5198215 | 0.68 | TGFBR1 (0.44) | — | |
| SCHEMBL26102188 | 0.67 | DGAT1 (0.43) | DGAT1ALOX5APFEN1 | |
| SCHEMBL5199026 | 0.67 | TGFBR1 (0.42) | DGAT1 | |
| SCHEMBL20401491 | 0.66 | DGAT1 (0.43) | DGAT1ALOX5APFEN1 | |
| SCHEMBL31104178 | 0.66 | DGAT1 (0.43) | DGAT1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275968-A1 | Substituted Biphenyl Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1798229-A1 | SUBSTITUTED BIPHENYL DERIVATIVE | Sankyo Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275968-A1 | Substituted Biphenyl Derivative | COL2A1, COL1A1, FGFR3 | DGAT1 3660/4885ALOX5AP 4019/4885FEN1 4807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.