SCHEMBL5199567

SCHEMBL5199567

SC1Nc2ccccc2N1Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.48
▸ ALOX12 P18054 2/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ HPGD P15428 2/20 0.40
▸ HTT P42858 2/20 0.40
▸ NPSR1 Q6W5P4 2/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ EPHX2 P34913 1/20 0.40
▸ EHMT2 Q96KQ7 1/20 0.40
▸ HDAC2 Q92769 3/20 0.39
▸ HDAC8 Q9BY41 3/20 0.39
▸ HDAC6 Q9UBN7 3/20 0.39
▸ SIGMAR1 Q99720 2/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7498201 0.81 LMNA (0.49) LMNAALOX12MAPK1MEN1KMT2A
SCHEMBL18535188 0.79 ALOX12 (0.55) LMNAALOX12MAPK1MEN1KMT2A
SCHEMBL17751142 0.79 LMNA (0.44) LMNAALOX12MAPK1MEN1KMT2A
SCHEMBL11350549 0.79 PTPN1 (0.34) LMNAALOX12MAPK1MEN1KMT2A
SCHEMBL11852030 0.78 ALDH1A1 (0.52) LMNAMEN1KMT2AKDM4EALDH1A1
SCHEMBL22726442 0.76 ALOX12 (0.48) LMNAALOX12MAPK1MEN1KMT2A
SCHEMBL13017916 0.69 RAB9A (0.36) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL14603003 0.69 LMNA (0.57) LMNAALOX12MAPK1MEN1KMT2A
SCHEMBL14279971 0.68 PTPN1 (0.41) ALOX12MAPK1MEN1KMT2AKDM4E
SCHEMBL19301758 0.68 PTPN1 (0.41) ALOX12MAPK1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1217432-B1 Silver halide photographic light-sensitive material and method for processing the same FUJIFILM CORP (JP) 2007-08-15 — — EP disclosed
US-6544718-B2 Hydrophilic colloid layer includes a disulfide or dimercapto compound of given formula; for photomechanical plate-making that exhibits ultrahigh-contrast photographic characteristics FUJI PHOTO FILM CO., LTD. (JP) 2003-04-08 — — US disclosed
US-20030022113-A1 Silver halide photographic light-sensitive material and method for processing same FUJI PHOTO FILM CO., LTD. 2003-01-30 — — US disclosed
EP-1217432-A2 Silver halide photographic light-sensitive material and method for processing the same FUJI PHOTO FILM CO., LTD. (JP) 2002-06-26 — — EP disclosed
US-6171753-B1 SUPPORT HAVING THEREON SPECTRALLY SENSITIZED LIGHT SENSITIVE SILVER HALIDE EMULSION LAYER CONTAINING AT LEAST TWO KINDS OF SILVER HALIDE EMULSIONS DIFFERENT IN THE CONCENTRATION OF A NITROGEN HETEROCYCLE CAPABLE OF FORMING COMPLEX WITH SILVER FUJI PHOTO FILM CO., LTD. (JP) 2001-01-09 — — US disclosed
US-6114081-A COMPRISING A SUPPORT HAVING THEREON AT LEAST ONE OF SPECTRALLY SENSITIZED LIGHT-SENSITIVE SILVER HALIDE EMULSION LAYERS, WHEREIN AT LEAST ONE OF THE SILVER HALIDE EMULSION LAYERS CONTAINS AT LEAST TWO KINDS OF SILVER HALIDE EMULSIONS FUJI PHOTO FILM CO., LTD. (JP) 2000-09-05 — — US disclosed
EP-0122125-B1 SILVER HALIDE EMULSION KONICA CORPORATION (JP) 1987-07-15 — — EP disclosed
US-4565778-A COMPRISING CORE/SHELL GRAINS OF SILVER IODOBROMIDE REPENED BY A LABILE SELENIUM COMPOUND;PHOTOSENSITIVITY;ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-01-21 — — US disclosed
EP-0122125-A1 Silver halide emulsion KONICA CORPORATION (JP) 1984-10-17 — — EP disclosed
EP-0121435-A1 Silver halide photographic materials KONICA CORPORATION (JP) 1984-10-10 — — EP disclosed
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