Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201332 | 0.92 | ALDH1A1 (0.50) | GAAALDH1A1GFERCYP4Z1NFKB1 | |
| SCHEMBL5100488 | 0.88 | ALDH1A1 (0.51) | GAAALDH1A1GFERCYP4Z1NFKB1 | |
| SCHEMBL25879759 | 0.87 | CYP4F2 (0.43) | GAAALDH1A1GFERCYP4Z1PKM | |
| SCHEMBL16413297 | 0.82 | GAA (0.52) | GAAALDH1A1GFERNFKB1TSHR | |
| SCHEMBL21437852 | 0.81 | NLRP3 (0.43) | GAAALDH1A1PKMNPC1RAB9A | |
| SCHEMBL2131319 | 0.81 | LMNA (0.46) | ALDH1A1PKMSMN1; SMN2TDP1KDM4E | |
| SCHEMBL20383846 | 0.80 | PKM (0.42) | ALDH1A1PKMSMN1; SMN2TDP1HSD17B10 | |
| SCHEMBL118588 | 0.80 | ALDH1A1 (0.53) | GAAALDH1A1GFERCYP4Z1NFKB1 | |
| SCHEMBL31287243 | 0.80 | ALDH1A1 (0.53) | GAAALDH1A1GFERCYP4Z1NFKB1 | |
| SCHEMBL5034285 | 0.79 | CYP4Z1 (0.59) | GAAALDH1A1CYP4Z1NFKB1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179532-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | EISAI R&D MAN CO LTD (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6573384-B1 | 1,4-substituted cyclic amine compound which is useful as a pharmaceutical, and an intermediate for the process | EISAI CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1179532-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | Eisai Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |