Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | GNA15 | P30679 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205144 | 0.88 | CACNA1B (0.44) | FFAR1CACNA1BGNA15PTGER3FFAR4 | |
| SCHEMBL5204934 | 0.83 | PTGES (0.39) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL5205774 | 0.82 | ADAMTS5 (0.40) | FFAR1PTGESALOX5PPARGPPARD | |
| SCHEMBL4010929 | 0.80 | PTGES (0.49) | FFAR1GNA15PTGER3FFAR4TDP1 | |
| SCHEMBL5205589 | 0.78 | CACNA1B (0.50) | CACNA1B | |
| SCHEMBL6180089 | 0.77 | FFAR1 (0.54) | FFAR1CACNA1BGNA15PTGER3FFAR4 | |
| SCHEMBL5203690 | 0.75 | FFAR1 (0.47) | FFAR1FFAR4 | |
| SCHEMBL5179510 | 0.72 | FFAR1 (0.60) | FFAR1CACNA1BGNA15PTGER3FFAR4 | |
| SCHEMBL4035951 | 0.71 | CACNA1B (0.59) | FFAR1CACNA1BGNA15PTGER3FFAR4 | |
| SCHEMBL2957633 | 0.71 | HSD17B1 (0.51) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |