Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GNA15 | P30679 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205144 | 0.91 | CACNA1B (0.44) | PTGESHDAC8HDAC1FFAR1ALOX5 | |
| SCHEMBL5205774 | 0.90 | ADAMTS5 (0.40) | PTGESHDAC8FFAR1ALOX5MEN1 | |
| SCHEMBL5201809 | 0.83 | FFAR1 (0.49) | PTGESFFAR1ALOX5GNA15PTGER3 | |
| SCHEMBL7834277 | 0.82 | FFAR1 (0.44) | HDAC8HDAC1FFAR1MEN1KMT2A | |
| SCHEMBL5205589 | 0.81 | CACNA1B (0.50) | MEN1KMT2AKDM4CKDM5B | |
| SCHEMBL6176321 | 0.80 | FFAR1 (0.42) | HDAC8HDAC1FFAR1MEN1KMT2A | |
| SCHEMBL5201777 | 0.79 | P2RY1 (0.43) | HDAC8FFAR1MEN1KMT2A | |
| SCHEMBL5205267 | 0.78 | MEN1 (0.41) | PTGESMEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL5205229 | 0.78 | PTGDR2 (0.37) | PTGESHDAC8FFAR1 | |
| SCHEMBL2957633 | 0.74 | HSD17B1 (0.51) | PTGESMEN1HTTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |