Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202338 | 0.81 | GFER (0.47) | HTR6USP2ALDH1A1RORCGFER | |
| SCHEMBL5937364 | 0.70 | ALDH1A1 (0.57) | USP2ALDH1A1RORCKDM4ELMNA | |
| SCHEMBL5705162 | 0.70 | RORC (0.51) | USP2ALDH1A1RORCCYP1A2CYP2C9 | |
| SCHEMBL4859112 | 0.68 | RORC (0.47) | HTR6USP2ALDH1A1RORCGFER | |
| SCHEMBL17067795 | 0.68 | ALDH1A1 (0.51) | USP2ALDH1A1DRD2SLC6A4HTR2A | |
| SCHEMBL18701720 | 0.67 | RORC (0.49) | USP2ALDH1A1RORCKDM4E | |
| SCHEMBL4858049 | 0.67 | MEN1 (0.52) | HTR6USP2ALDH1A1RORCCHRM2 | |
| SCHEMBL5201722 | 0.67 | HTR2B (0.53) | USP2ALDH1A1RORCLMNA | |
| SCHEMBL4858050 | 0.66 | RAB9A (0.62) | ALDH1A1RORCKDM4ELMNA | |
| SCHEMBL26912621 | 0.66 | GSK3B (0.46) | USP2ALDH1A1DRD2SLC6A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654253-B1 | SUBSTITUTED 3-PYRROLIDIN-INDOLE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-01-03 | — | — | EP | claimed |