Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25493940 | 1.00 | CA1 (0.39) | CA1CA2CA4MAPT | |
| SCHEMBL22627299 | 1.00 | CA1 (0.39) | CA1CA2CA4MAPT | |
| SCHEMBL14840983 | 0.79 | MAPT (0.32) | MAPT | |
| SCHEMBL14840982 | 0.79 | MAPT (0.32) | MAPT | |
| SCHEMBL21001033 | 0.76 | CA1 (0.33) | CA1CA2CA4MAPT | |
| SCHEMBL21001228 | 0.70 | — | — | |
| SCHEMBL5199760 | 0.69 | GAA (0.32) | MAPT | |
| SCHEMBL19433861 | 0.69 | CYP1A2 (0.34) | — | |
| SCHEMBL1382052 | 0.69 | CA1 (0.40) | CA1CA2CA4MAPT | |
| SCHEMBL5155621 | 0.69 | CA1 (0.40) | CA1CA2CA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066690-A1 | Spiro Compounds as Malodor Counteracting Ingredients | FIRMENICH SA (CH) | 2025-02-27 | — | — | US | claimed |
| US-20230233425-A1 | USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR | FIRMENICH SA (CH) | 2023-07-27 | — | — | US | claimed |
| US-20230159853-A1 | SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2023-05-25 | — | — | US | claimed |
| EP-1411110-B1 | Spiro compounds as perfuming ingredients | FIRMENICH & CIE (CH) | 2007-08-22 | — | — | EP | claimed |
| EP-4707270-A2 | SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS | Firmenich SA (CH) | 2026-03-11 | — | — | EP | disclosed |
| EP-4632382-A2 | METHOD OF IDENTIFYING LAUNDRY MALODOR, MOLDY MALODOR AND/OR SWEAT MALODOR MODULATING COMPOUNDS | Firmenich SA (CH) | 2025-10-15 | — | — | EP | disclosed |
| EP-3713609-B1 | SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH & CIE (CH) | 2025-08-06 | — | — | EP | disclosed |
| US-20250066690-A1 | Spiro Compounds as Malodor Counteracting Ingredients | FIRMENICH SA (CH) | 2025-02-27 | — | — | US | disclosed |
| US-12180434-B2 | Spiro compounds as malodor counteracting ingredients | FIRMENICH SA (CH) | 2024-12-31 | — | — | US | disclosed |
| US-11744785-B2 | Use of volatile compositions to limit or eliminate the perception of malodor | FIRMENICH SA (CH) | 2023-09-05 | — | — | US | disclosed |
| US-20230233425-A1 | USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR | FIRMENICH SA (CH) | 2023-07-27 | — | — | US | disclosed |
| US-20230159853-A1 | SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11744785-B2 | Use of volatile compositions to limit or eliminate the perception of malodor | TAS2R8, TRPA1, TAS2R10 | CA1 4530/4885CA2 1444/4885CA4 1031/4885 |
| US-20250066690-A1 | Spiro Compounds as Malodor Counteracting Ingredients | LPO, SORD, FOXO1 | CA1 4453/4885CA2 2955/4885CA4 1842/4885 |
| US-20230233425-A1 | USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR | TAS2R8, TRPA1, TAS2R10 | CA1 4530/4885CA2 1444/4885CA4 1031/4885 |
| US-12180434-B2 | Spiro compounds as malodor counteracting ingredients | LPO, SORD, FOXO1 | CA1 4453/4885CA2 2955/4885CA4 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.