Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 6/20 | 0.58 |
| ▸ | LDHB | P07195 | 6/20 | 0.58 |
| ▸ | HAO1 | Q9UJM8 | 5/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330660 | 0.85 | ACMSD (0.66) | MCL1ACMSDDHFRHNF4ALCK | |
| SCHEMBL31074035 | 0.82 | LDHA (0.49) | LDHALDHBHAO1AKT1PTGS2 | |
| SCHEMBL38656046 | 0.81 | LDHA (0.57) | LDHALDHBHAO1AKT1MCL1 | |
| SCHEMBL5203748 | 0.79 | SRD5A2 (0.62) | — | |
| SCHEMBL130628 | 0.78 | ALDH1A1 (0.59) | MCL1ACMSDDHFRHNF4APTGS2 | |
| SCHEMBL3992190 | 0.77 | RXRA (0.65) | MCL1ACMSDDHFRHNF4APTGS2 | |
| SCHEMBL5209176 | 0.77 | KDM4E (0.56) | AR | |
| SCHEMBL5204502 | 0.77 | KDM4E (0.51) | — | |
| SCHEMBL10786191 | 0.76 | ALDH1A1 (0.58) | MCL1ACMSDDHFRHNF4APTGS2 | |
| SCHEMBL3744237 | 0.75 | ALDH1A1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | LDHA 2293/4885LDHB 2140/4885HAO1 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.