Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5200567 | 0.94 | ADRA1A (0.38) | ADRA1AADRA2AHRH3MEN1ALDH1A1 | |
| SCHEMBL5201429 | 0.82 | ADRA1A (0.48) | ADRA1AADRA2AHRH3MEN1ALDH1A1 | |
| SCHEMBL5206471 | 0.75 | ADRA2A (0.54) | ADRA1AADRA2AHRH3MEN1ALDH1A1 | |
| SCHEMBL5200584 | 0.74 | ADRA2A (0.32) | ADRA1AADRA2A | |
| SCHEMBL7101637 | 0.74 | NR3C1 (0.39) | NR3C1PTGS1 | |
| SCHEMBL5203578 | 0.74 | ADRA1A (0.53) | ADRA1AADRA2AHRH3MAPTHRH4 | |
| SCHEMBL5200544 | 0.71 | ADRA1A (0.48) | ADRA1AADRA2AHRH3NR3C1ADRA1D | |
| Hydrochloric Acid SCHEMBL5201568 | 0.70 | ADRA1A (0.47) | ADRA1AADRA2AHRH3MAPTNR3C1 | |
| SCHEMBL17922097 | 0.65 | HRH3 (0.61) | HRH3MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7100325 | 0.65 | NR3C1 (0.37) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887346-B1 | N-Phenyl-alkylsulfonamide derivatives, their preparation and their use as alpha1A/1L adrenoceptor agonists | HOFFMANN LA ROCHE (CH) | 2007-12-12 | — | — | EP | disclosed |