SCHEMBL5204866

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5379969	0.85	ALDH1A1 (0.51)	ALDH1A1MAPK1GPR183SMN1; SMN2NPC1
	SCHEMBL16329717	0.83	MEN1 (0.47)	ALDH1A1MAPK1GPR183SMN1; SMN2NPC1
	SCHEMBL14907918	0.80	MEN1 (0.51)	ALDH1A1GPR183SMN1; SMN2NPC1RAB9A
	SCHEMBL861568	0.76	RAB9A (0.52)	ALDH1A1GPR183SMN1; SMN2NPC1RAB9A
	SCHEMBL8288520	0.74	GPR183 (0.56)	ALDH1A1GPR183SMN1; SMN2NPC1RAB9A
	SCHEMBL11491058	0.73	MAOB (0.62)	ALDH1A1MAPK1GPR183SMN1; SMN2NPC1
	SCHEMBL4656696	0.73	CYP3A4 (0.45)	ALDH1A1MAPK1HTR3EHTR3BHTR3A
	SCHEMBL2156716	0.72	ALDH1A1 (0.50)	ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
	SCHEMBL2155635	0.72	CYP3A4 (0.46)	ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A
	SCHEMBL97197	0.72	NPC1 (0.48)	ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.