Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030269 | 0.87 | TSHR (0.46) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL97119 | 0.83 | NPC1 (0.45) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9669171 | 0.82 | SMN1; SMN2 (0.37) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2156716 | 0.79 | ALDH1A1 (0.50) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL140150 | 0.78 | MAPT (0.51) | KMT2ASMN1; SMN2MEN1POLBALDH1A1 | |
| SCHEMBL30300332 | 0.78 | MAPT (0.51) | KMT2ASMN1; SMN2MEN1POLBALDH1A1 | |
| SCHEMBL6018971 | 0.78 | CYP3A4 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9432285 | 0.78 | CYP3A4 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10745644 | 0.78 | MIF (0.49) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL861172 | 0.78 | CYP3A4 (0.48) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070864-A1 | Quinazolinone Modulators Of Nuclear Receptors | X-CEPTOR THERAPEUTICS, INC. (US) | 2008-03-20 | — | — | US | claimed |
| US-20070203138-A1 | Novel Compounds and Compositions as Cathepsin S Inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-08-30 | — | — | US | claimed |
| US-7238700-B2 | A2B adenosine receptor antagonists | CV THERAPEUTICS, INC. (US) | 2007-07-03 | — | — | US | claimed |
| US-20070135386-A1 | Novel Compounds and Compositions as Cathepsin Inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-06-14 | — | — | US | claimed |
| US-7226921-B2 | Compounds and compositions as cathepsin S inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-06-05 | — | — | US | claimed |
| US-7196099-B2 | Compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-27 | — | — | US | claimed |
| EP-1501504-B1 | 1-SUBSTITUTED IMIDAZOLE DERIVATIVES AS NOS INHIBITORS | SCHERING AG (DE) | 2007-02-07 | — | — | EP | claimed |
| US-6982259-B2 | N-heterocyclic derivatives as NOS inhibitors | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-01-03 | — | — | US | claimed |
| US-6977256-B2 | Compounds and compositions as cathepsin S inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-20 | — | — | US | claimed |
| US-20050267044-A1 | Novel compounds and compositions as cathepsin S inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-01 | — | — | US | claimed |
| WO-1999023090-A1 | NOVEL GENIPIN DERIVATIVE HAVING LIVER PROTECTION ACTIVITY | CHOONGWAE PHARMA CORPORATION (KR) | 1999-05-14 | — | — | WO | claimed |
| WO-1994014765-A1 | CYCLOHEXYLSULFONYL-ACRYLIC ACID AND ITS DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1994-07-07 | — | — | WO | claimed |
| US-5206363-A | PROCESS FOR THE RESOLUTION OF ENANTIOMERS OF 5-HETEROARYL-1,3,4-THIADIAZINONES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | claimed |
| EP-0150507-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR PRODUCING THE SAME AND COMPOSITIONS CONTAINING THEM | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-05 | — | — | EP | claimed |
| US-4916128-A | Thiadiazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | claimed |
| US-4888332-A | ANTIBIOTICS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-19 | — | — | US | claimed |
| EP-0150507-A2 | Cephalosporin derivatives, processes for producing the same and compositions containing them | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1985-08-07 | — | — | EP | claimed |
| US-4472386-A | 5-Fluoro-(β-uridine or 2'-deoxy-β-uridine) derivatives, a process for producing the same and a carcinostatic agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | claimed |
| US-4083981-A | INDOLE-3-ACETIC ACID DERIVATIVES AND NARCOTIC | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-11 | — | — | US | claimed |
| US-4029798-A | SYNERGISTIC MIXTURE OF INDOLE-3-ACETIC ACID DERIVATIVE AND NARCOTIC | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-06-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267044-A1 | Novel compounds and compositions as cathepsin S inhibitors | CTSS, CTSB, CTSE | NPC1 40/4885RAB9A 494/4885KMT2A 4617/4885 |
| US-20070203138-A1 | Novel Compounds and Compositions as Cathepsin S Inhibitors | CTSS, CTSB, CTSE | NPC1 40/4885RAB9A 494/4885KMT2A 4617/4885 |
| US-20070135386-A1 | Novel Compounds and Compositions as Cathepsin Inhibitors | CTSS, CTSB, CTSE | NPC1 36/4885RAB9A 448/4885KMT2A 4602/4885 |
| US-20080070864-A1 | Quinazolinone Modulators Of Nuclear Receptors | NR1H4, NR1H2, NR1H3 | NPC1 84/4885RAB9A 1349/4885KMT2A 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.