Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.30 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5206023 | 0.85 | ENPP2 (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL5211197 | 0.85 | FLT3 (0.36) | MAPTTP53NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5203620 | 0.85 | PIK3CA (0.33) | MAPTTP53SMN1; SMN2NPC1PKM | |
| SCHEMBL5210132 | 0.83 | F2 (0.39) | MAPTTP53SMN1; SMN2NPC1PKM | |
| Trifluoroacetic Acid SCHEMBL5208294 | 0.83 | MEN1 (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL5208796 | 0.83 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| Trifluoroacetic Acid SCHEMBL5209196 | 0.82 | IKBKB (0.33) | F2 | |
| Trifluoroacetic Acid SCHEMBL5209741 | 0.82 | PDE4D (0.38) | MAPTTP53LMNA | |
| SCHEMBL6991435 | 0.80 | F2 (0.35) | MAPTTP53SMN1; SMN2NPC1PKM | |
| Hydrochloric Acid SCHEMBL5208877 | 0.79 | PIK3CA (0.35) | MAPTTP53SMN1; SMN2NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |