Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | P2RY10 | O00398 | 3/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343970 | 0.82 | HSD11B1 (0.34) | ALDH1A1KDM4ELMNA | |
| SCHEMBL2728740 | 0.69 | CYP4F2 (0.52) | ALDH1A1P2RY10GPR34LMNATSHR | |
| SCHEMBL11666453 | 0.67 | ELANE (0.43) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL4639413 | 0.67 | LIPG (0.41) | — | |
| SCHEMBL9601334 | 0.67 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL717427 | 0.67 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL7645989 | 0.66 | GAA (0.38) | ALDH1A1KDM4EGAAKMT2ATSHR | |
| SCHEMBL6064915 | 0.66 | MEN1 (0.39) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL15796532 | 0.66 | TSHR (0.48) | ALDH1A1KDM4EP2RY10GPR34LMNA | |
| SCHEMBL4238151 | 0.66 | MAOA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853660-A1 | STABILIZATION OF POLYOL OR POLYURETHANE COMPOSITIONS AGAINST THERMAL OXIDATION | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006092363-A1 | STABILIZATION OF POLYOL OR POLYURETHANE COMPOSITIONS AGAINST THERMAL OXIDATION | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-09-08 | — | — | WO | disclosed |