Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032402 | 0.90 | LOXL2 (0.50) | MAOBMAOANPC1GAARAB9A | |
| SCHEMBL6435082 | 0.90 | NPC1 (0.44) | MAOBMAOASNCATSHRNPC1 | |
| SCHEMBL4304998 | 0.90 | NPC1 (0.44) | MAOBMAOASNCATSHRNPC1 | |
| SCHEMBL7666461 | 0.81 | CYP2A6 (0.68) | MAOBMAOATSHRGAASMN1; SMN2 | |
| SCHEMBL3410482 | 0.81 | MAOA (0.56) | MAOBMAOATSHRSMN1; SMN2MAPT | |
| SCHEMBL69726 | 0.79 | MAOB (0.57) | MAOBMAOATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10804609 | 0.78 | MAOB (0.44) | MAOBMAOAGAAMAPTALDH1A1 | |
| SCHEMBL8712652 | 0.75 | MAOB (0.48) | MAOBTSHRGAAMAPTALDH1A1 | |
| SCHEMBL19437177 | 0.74 | MAOB (0.41) | MAOBMAOAGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL654153 | 0.74 | NFE2L2 (0.52) | MAOBTSHRSMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556372-B1 | SUBSTITUTED 4-AMINO-1-(PYRIDYLMETHYL) PIPERIDINE AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE INC (US) | 2007-05-30 | — | — | EP | claimed |