Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 4/20 | 1.00 |
| ▸ | TRPC3 | Q13507 | 3/20 | 0.61 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.61 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.61 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321880 | 1.00 | ORAI1 (1.00) | ORAI1TRPC3TRPC1STIM1TRPC5 | |
| SCHEMBL7316335 | 0.91 | ORAI1 (0.83) | ORAI1TRPC3TRPC1STIM1TRPC5 | |
| SCHEMBL7319652 | 0.89 | ORAI1 (0.81) | ORAI1TRPC3TRPC1STIM1TRPC5 | |
| SCHEMBL7327988 | 0.89 | ORAI1 (0.81) | ORAI1TRPC3TRPC1STIM1TRPC5 | |
| SCHEMBL7326875 | 0.89 | ORAI1 (0.81) | ORAI1TRPC3TRPC1STIM1TRPC5 | |
| SCHEMBL7317754 | 0.89 | ORAI1 (0.81) | ORAI1TRPC3TRPC1STIM1TRPC5 | |
| SCHEMBL7318374 | 0.89 | ORAI1 (0.80) | ORAI1TRPC3TRPC1STIM1TRPC5 | |
| SCHEMBL7315257 | 0.88 | ORAI1 (0.79) | ORAI1TRPC3TRPC1STIM1TRPC5 | |
| SCHEMBL7315232 | 0.88 | ORAI1 (0.79) | ORAI1TRPC3TRPC1STIM1TRPC5 | |
| SCHEMBL7317288 | 0.88 | ORAI1 (0.79) | ORAI1TRPC3TRPC1STIM1TRPC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722696-A1 | METHOD AND SYSTEM FOR PERFORMING TIME-CORRELATED SINGLE PHOTON COUNTING MEASUREMENTS | Prospective Instruments GmbH (CH) | 2026-04-08 | — | — | EP | claimed |
| US-12365945-B2 | Urinary microbiomic profiling | Convergent Genomics, Inc. (US) | 2025-07-22 | — | — | US | claimed |
| CN-119783003-A | Industrial production safety management system based on Internet | 吉林市合达网络科技有限公司 | 2025-04-08 | — | — | CN | claimed |
| US-20250009891-A1 | CONJUGATES OF MONOCYCLIC BETA-LACTAMS AND SIDEROPHORE MIMETICS | UNIVERSITY OF NOTRE DAME DU LAC | 2025-01-09 | — | — | US | claimed |
| CN-112331789-B | Electroluminescent device | 广东聚华印刷显示技术有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-114253133-A | Sliding mode fault-tolerant control method and device based on dynamic event trigger mechanism | 北京科技大学 | 2022-03-29 | — | — | CN | claimed |
| WO-2022047234-A1 | DRUG COMBINATION KITS AND METHODS OF DRUG DELIVERY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-03-03 | — | — | WO | claimed |
| US-12613596-B2 | Display device | SAMSUNG DISPLAY CO., LTD. (KR) | 2026-04-28 | — | — | US | disclosed |
| US-12613603-B2 | Display device | SAMSUNG DISPLAY CO., LTD. (KR) | 2026-04-28 | — | — | US | disclosed |
| US-20260112967-A1 | CHARGE PUMP FOR GATE DRIVER CIRCUIT | TEXAS INSTRUMENTS INC (US) | 2026-04-23 | — | — | US | disclosed |
| EP-4722696-A1 | METHOD AND SYSTEM FOR PERFORMING TIME-CORRELATED SINGLE PHOTON COUNTING MEASUREMENTS | Prospective Instruments GmbH (CH) | 2026-04-08 | — | — | EP | disclosed |
| US-12544371-B2 | Methods and compositions for treating acute lung injury and acute respiratory distress syndrome | CALCIMEDICA, INC. (US) | 2026-02-10 | — | — | US | disclosed |
| US-20250306722-A1 | DISPLAY DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2025-10-02 | — | — | US | disclosed |
| US-6958339-B2 | Pyrazole derivative | ASTELLAS PHARMA INC. (JP) | 2005-10-25 | — | — | US | disclosed |
| US-20050234055-A1 | Pyrazole derivative | ASTELLAS PHARMA INC. | 2005-10-20 | — | — | US | disclosed |
| US-6506747-B1 | Method of treating an inflammatory disease which comprises administering to a patient in need of such treatment-a N-(4-(5-Ethyl-3-pyridin-3-yl-pyrazol-1-yl)phenyl)pyridine-3-carboxamide; | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | disclosed |
| US-6348480-B1 | CALCIUM CHANNEL BLOCKERS AND ANTIINFLAMMATORY AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| US-20010011090-A1 | Pyrazole derivative | ASTELLAS PHARMA INC. (JP) | 2001-08-02 | — | — | US | disclosed |
| EP-1024138-A1 | PYRAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999062885-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)PYRAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12544371-B2 | Methods and compositions for treating acute lung injury and acute respiratory distress syndrome | ORAI1, MAVS, CASR | ORAI1 1/4885TRPC3 219/4885TRPC1 477/4885 |
| US-20050234055-A1 | Pyrazole derivative | RYR2, RYR1, NR1I3 | ORAI1 15/4885TRPC3 6/4885TRPC1 77/4885 |
| US-20250009891-A1 | CONJUGATES OF MONOCYCLIC BETA-LACTAMS AND SIDEROPHORE MIMETICS | MGAM, OPRM1, BPGM | ORAI1 226/4885TRPC3 3702/4885TRPC1 1147/4885 |
| US-12613596-B2 | Display device | EPHA8, NCS1, EPHA4 | ORAI1 495/4885TRPC3 1930/4885TRPC1 587/4885 |
| US-20260112967-A1 | CHARGE PUMP FOR GATE DRIVER CIRCUIT | HCN1, CDC25A, CDC25B | ORAI1 19/4885TRPC3 2169/4885TRPC1 161/4885 |
| US-20010011090-A1 | Pyrazole derivative | RYR1, CACNA1E, RYR2 | ORAI1 22/4885TRPC3 32/4885TRPC1 43/4885 |
| US-12613603-B2 | Display device | EPHA8, EPHA4, NCS1 | ORAI1 1394/4885TRPC3 984/4885TRPC1 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.