Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25022177 | 0.94 | PRCP (0.61) | PRCPNAAAEPHX1EPHX2GNAI3 | |
| SCHEMBL5193732 | 0.85 | EPHX1 (0.47) | PRCPNAAAEPHX1EPHX2 | |
| SCHEMBL6050265 | 0.83 | FDPS (0.44) | PRCPEPHX1 | |
| SCHEMBL5192295 | 0.78 | CCR2 (0.41) | PRCP | |
| SCHEMBL2240203 | 0.77 | OTC (0.47) | — | |
| SCHEMBL28102652 | 0.77 | OTC (0.47) | — | |
| SCHEMBL10927718 | 0.76 | GNAI3 (0.50) | PRCPGNAI3GNAO1GNAI1 | |
| SCHEMBL8847557 | 0.76 | KEAP1 (0.60) | NAAAEPHX1EPHX2CASP2 | |
| SCHEMBL3231149 | 0.76 | PRCP (0.88) | PRCPNAAAEPHX1EPHX2GNAI3 | |
| SCHEMBL12196017 | 0.75 | NAAA (0.61) | NAAAEPHX1EPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |
| EP-0215477-A1 | Process and intermediates for antiarrhytmic 1,3-diazabicyclo/4.4.0/dec-2-en-4-ones | G.D. Searle & Co. (US) | 1987-03-25 | — | — | EP | claimed |