Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FABP6 | P51161 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195397 | 0.81 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL5194848 | 0.80 | OPRK1 (0.46) | SIGMAR1GAAL3MBTL1POLB | |
| SCHEMBL5193908 | 0.78 | LMNA (0.42) | GAA | |
| SCHEMBL25154270 | 0.77 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL25154734 | 0.77 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL5191215 | 0.76 | FAAH (0.60) | — | |
| SCHEMBL26639370 | 0.75 | SMN1; SMN2 (0.33) | SIGMAR1L3MBTL1 | |
| SCHEMBL5191126 | 0.75 | SMN1; SMN2 (0.48) | POLB | |
| SCHEMBL5192001 | 0.73 | SIGMAR1 (0.56) | SIGMAR1GAAL3MBTL1POLB | |
| SCHEMBL10681973 | 0.73 | SIGMAR1 (0.55) | SIGMAR1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |