Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | LDHA | P00338 | 1/20 | 0.57 |
| ▸ | LDHB | P07195 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406029 | 0.88 | HTT (0.58) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL20922083 | 0.86 | HTT (0.66) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL16204421 | 0.86 | HTT (0.60) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL483939 | 0.85 | LDHA (0.56) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL6988691 | 0.85 | HTT (0.67) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL13263349 | 0.84 | NPC1 (0.62) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL21479386 | 0.83 | KDM4E (0.75) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL15546417 | 0.82 | NPC1 (0.69) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL30771563 | 0.81 | NPC1 (0.61) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL2152084 | 0.81 | NPC1 (0.61) | HTTNPC1RAB9AKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115902018-A | Detection method of linezolid isomer | 江苏晨牌药业集团股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-RE47606-E1 | Process for the preparation of linezolid | OPTIMUS DRUGS PRIVATE LIMITED (IN) | 2019-09-17 | — | — | US | disclosed |
| WO-2017182853-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LINEZOLID | OPTIMUS DRUGS PVT LTD (IN) | 2017-10-26 | — | — | WO | disclosed |
| US-9643939-B1 | Process for the preparation of linezolid | OPTIMUS DRUGS PRIVATE LIMITED (US) | 2017-05-09 | — | — | US | disclosed |
| US-9643939-B1 | Process for the preparation of linezolid | OPTIMUS DRUGS PRIVATE LIMITED (US) | 2017-05-09 | — | — | US | disclosed |
| US-9586913-B2 | Processes for the preparation of linezolid using novel intermediates | SYMED LABS LIMITED (IN) | 2017-03-07 | — | — | US | disclosed |
| US-20160102064-A1 | IMPROVED PROCESSES FOR THE PREPARATION OF LINEZOLID USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2016-04-14 | — | — | US | disclosed |
| WO-2014174522-A1 | IMPROVED PROCESSES FOR THE PREPARATION OF LINEZOLID USING NOVEL INTERMEDIATES | SYMED LABS LIMITED (IN) | 2014-10-30 | — | — | WO | disclosed |
| EP-1028940-B1 | PROCESS TO PRODUCE OXAZOLIDINONES | PHARMACIA & UPJOHN CO LLC (US) | 2007-04-18 | — | — | EP | disclosed |
| EP-1772453-A1 | Process to produce Oxazolidinones | Pharmacia & Upjohn Company LLC (US) | 2007-04-11 | — | — | EP | disclosed |
| US-6492555-B2 | REACTION OF A CARBAMATE WITH EITHER A (S)-SECONDARY ALCOHOL OR (S)-EPOXIDE OR (S)-ESTER; BACTERICIDES | PHARMACIA & UPJOHN COMPANY | 2002-12-10 | — | — | US | disclosed |
| US-20020095054-A1 | Process to produce oxazolidinones | PHARMACIA & UPJOHN COMPANY | 2002-07-18 | — | — | US | disclosed |
| US-20020086900-A1 | Methods of producing oxazolidinone compounds | PERRAULT WILLIAM R (US) | 2002-07-04 | — | — | US | disclosed |
| US-6410788-B1 | BACTERICIDES; REACTING IMINE, CARBAMATE, ESTER, AMIDE AND EPOXIDE DERIVATIVES | PHARMACIA & UPJOHN COMPANY | 2002-06-25 | — | — | US | disclosed |
| WO-2002032857-A1 | METHODS OF PRODUCING OXAZOLIDINONE COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-04-25 | — | — | WO | disclosed |
| US-6362334-B1 | OXAZOLIDINONE PHTHALAMIDE | PHARMACIA & UPJOHN COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-20020032348-A1 | Process to produce oxazolidinones | PEARLMAN BRUCE ALLEN (US) | 2002-03-14 | — | — | US | disclosed |
| EP-1028940-A1 | PROCESS TO PRODUCE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| US-6107519-A | Process to produce oxazolidinones | PHARMACIA & UPJOHN COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| WO-1999024393-A1 | PROCESS TO PRODUCE OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 1999-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102064-A1 | IMPROVED PROCESSES FOR THE PREPARATION OF LINEZOLID USING NOVEL INTERMEDIATES | CYP3A5, SBDS, MLYCD | HTT 3785/4885NPC1 3226/4885RAB9A 2934/4885 |
| US-20020095054-A1 | Process to produce oxazolidinones | ADH1A, ADH5, ADH1C | HTT 3874/4885NPC1 3095/4885RAB9A 3277/4885 |
| US-20020086900-A1 | Methods of producing oxazolidinone compounds | TET3, TET1, AZI2 | HTT 559/4885NPC1 3328/4885RAB9A 4755/4885 |
| US-20020032348-A1 | Process to produce oxazolidinones | ADH1A, ADH5, ADH1C | HTT 3874/4885NPC1 3095/4885RAB9A 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.