Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | KYAT1 | Q16773 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056904 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TRPA1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL5221727 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TRPA1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL16649939 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TRPA1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL16649938 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TRPA1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL8502881 | 0.81 | GSK3B (0.33) | ALDH1A1TRPA1EGLN1 | |
| SCHEMBL10753700 | 0.81 | GSK3B (0.33) | ALDH1A1TRPA1EGLN1 | |
| SCHEMBL5798093 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TRPA1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL1135738 | 0.79 | APOBEC3A (0.53) | ALDH1A1TRPA1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL1135736 | 0.79 | APOBEC3A (0.53) | ALDH1A1TRPA1APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL19168953 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TRPA1APOBEC3AAPOBEC3GMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718790-B2 | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same | SHIONOGI & CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-9497966-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-11-22 | — | — | US | disclosed |
| US-9497966-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-11-22 | — | — | US | disclosed |
| EP-3060047-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | Dow AgroSciences, LLC (US) | 2016-08-31 | — | — | EP | disclosed |
| EP-2604595-B1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | SHIONOGI & CO (JP) | 2016-03-16 | — | — | EP | disclosed |
| CN-103153968-B | Triazole derivative and pharmaceutical composition containing same and having analgesic effect | SHIONOGI & CO.,LTD. (JP) | 2016-02-03 | — | — | CN | disclosed |
| WO-2015061157-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2015-04-30 | — | — | WO | disclosed |
| US-20150111732-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| US-20150111732-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| US-20130338367-A1 | PYRAZOLE DERIVATIVES AND PESTICIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-12-19 | — | — | US | disclosed |
| EP-2674423-A1 | PYRAZOLE DERIVATIVE AND PEST CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2013-12-18 | — | — | EP | disclosed |
| US-20130172317-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION HAVING AN ANALGESIC ACTIVITY COMPRISING THE SAME | SHIONOGI & CO., LTD. (JP) | 2013-07-04 | — | — | US | disclosed |
| EP-2604595-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | Shionogi&Co., Ltd. (JP) | 2013-06-19 | — | — | EP | disclosed |
| CN-103153968-A | Triazole derivative and pharmaceutical composition containing same and having analgesic effect | SHIONOGI & CO | 2013-06-12 | — | — | CN | disclosed |
| EP-1464642-B1 | NOVEL SUBSTITUTED PYRAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND HERBICIDAL COMPOSITION CONTAINING THE SAME | SDS BIOTECH CORP (JP) | 2007-08-29 | — | — | EP | disclosed |
| US-7192906-B2 | Substituted pyrazole derivatives, production process thereof, and herbicide compositions containing the derivatives | SDS BIOTECH K.K. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20050014649-A1 | Novel substituted pyrazole derivative, process for producing the same, and herbicidal composition containing the same | SDS BIOTECH K.K. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1464642-A1 | NOVEL SUBSTITUTED PYRAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND HERBICIDAL COMPOSITION CONTAINING THE SAME | SDS Biotech K.K. (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-5977355-A | Processes and intermediates for preparing 3-amino-benzo(b)azepinones | PFIZER INC. (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0209237-A2 | Vinyl-glycyl-amino-beta-lactam derivatives | BEECHAM GROUP PLC (GB) | 1987-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338367-A1 | PYRAZOLE DERIVATIVES AND PESTICIDES | CHRM1, CHRM2, CHRM3 | ALDH1A1 686/4885TRPA1 2247/4885APOBEC3A 1303/4885 |
| US-20150111732-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | ACHE, PRDX1, PRDX2 | ALDH1A1 3099/4885TRPA1 210/4885APOBEC3A 2535/4885 |
| US-20050014649-A1 | Novel substituted pyrazole derivative, process for producing the same, and herbicidal composition containing the same | HPD, HDHD5, CYP2E1 | ALDH1A1 296/4885TRPA1 403/4885APOBEC3A 1649/4885 |
| US-20130172317-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION HAVING AN ANALGESIC ACTIVITY COMPRISING THE SAME | P2RX3, P2RX4, P2RX2 | ALDH1A1 2167/4885TRPA1 77/4885APOBEC3A 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.