SCHEMBL5223027

SCHEMBL5223027

CCC(CO)(CO)COC(=O)CCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.31
PSMB5 P28074 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2589615 0.91 ALDH1A1 (0.32) PSMB8PSMB5
SCHEMBL2593467 0.86 PSMB8 (0.30) PSMB8PSMB5
SCHEMBL5223031 0.84 PSMB8 (0.34) PSMB8PSMB5
SCHEMBL27701450 0.80 PSMB8 (0.30) PSMB8PSMB5
SCHEMBL14948533 0.79 TSHR (0.43)
SCHEMBL14644916 0.78 PSMB8 (0.33) PSMB8PSMB5
SCHEMBL2589620 0.78 PSMB8 (0.34) PSMB8PSMB5
SCHEMBL18541146 0.77 PSMB8 (0.30) PSMB8PSMB5
SCHEMBL18309143 0.77 SMN1; SMN2 (0.38) MAPT
SCHEMBL43576 0.76 PSMB8 (0.35) PSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1824414-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MicroVention, Inc. (US) 2007-08-29 EP claimed
US-7201918-B2 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2007-04-10 US claimed
WO-2006055690-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MICROVENTION, INC. (US) 2006-05-26 WO claimed
US-20060105014-A1 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2006-05-18 US claimed
EP-1824414-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MicroVention, Inc. (US) 2007-08-29 EP disclosed
US-7201918-B2 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2007-04-10 US disclosed
WO-2006055690-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MICROVENTION, INC. (US) 2006-05-26 WO disclosed
US-20060105014-A1 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2006-05-18 US disclosed