SCHEMBL2589615

SCHEMBL2589615

O=C(CCC(=O)ON1C(=O)CCC1=O)OCC(CO)(CO)CO

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
PSMB8 P28062 1/20 0.31
PSMB5 P28074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2593467 0.94 PSMB8 (0.30) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL5223027 0.91 PSMB8 (0.31) PSMB8PSMB5
SCHEMBL27701450 0.85 PSMB8 (0.30) PSMB8PSMB5
SCHEMBL14644916 0.83 PSMB8 (0.33) PSMB8PSMB5
SCHEMBL2589620 0.83 PSMB8 (0.34) PSMB8PSMB5
SCHEMBL43576 0.81 PSMB8 (0.35) MAPK1SMN1; SMN2PSMB8PSMB5
SCHEMBL15760606 0.80 PSMB8 (0.31) PSMB8PSMB5
SCHEMBL141048 0.80 ADRA2A (0.36) ALDH1A1SMN1; SMN2PSMB8PSMB5
Ethylene Glycol SCHEMBL999673 0.79 PSMB8 (0.36) PSMB8PSMB5
SCHEMBL20713864 0.79 GSTP1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION THERAGENICS CORPORATION 2019-08-29 US claimed
US-10189773-B2 In-vivo gelling pharmaceutical pre-formulation MEDICUS BIOSCIENCES, LLC (US) 2019-01-29 US claimed
EP-2846847-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT Medicus Biosciences LLC (US) 2015-03-18 EP claimed
WO-2013170195-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES, LLC (US) 2013-11-14 WO claimed
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2013-05-09 US claimed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO claimed
EP-1824414-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MicroVention, Inc. (US) 2007-08-29 EP claimed
US-7201918-B2 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2007-04-10 US claimed
WO-2006055690-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MICROVENTION, INC. (US) 2006-05-26 WO claimed
US-20060105014-A1 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2006-05-18 US claimed
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT AQUARIAN CREDIT FUNDING LLC 2023-07-13 US disclosed
EP-2968680-B1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION C P MEDICAL CORP (US) 2023-05-03 EP disclosed
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment AQUARIAN CREDIT FUNDING LLC 2023-03-07 US disclosed
US-20210322785-A1 COMPOSITIONS AND METHODS FOR TREATING WOUNDS THERAGENICS CORPORATION 2021-10-21 US disclosed
EP-3893785-A1 COMPOSITIONS AND METHODS FOR TREATING WOUNDS C.P. Medical Corporation (US) 2021-10-20 EP disclosed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO disclosed
EP-1824414-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MicroVention, Inc. (US) 2007-08-29 EP disclosed
US-7201918-B2 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2007-04-10 US disclosed
WO-2006055690-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MICROVENTION, INC. (US) 2006-05-26 WO disclosed
US-20060105014-A1 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2006-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189773-B2 In-vivo gelling pharmaceutical pre-formulation FURIN, ARFGAP1, MGST1 ALDH1A1 84/4885TP53 1611/4885CYP3A4 339/4885
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT ALDH1A2, RB1, UACA ALDH1A1 297/4885TP53 2618/4885CYP3A4 4794/4885
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment ALDH1A2, RB1, UACA ALDH1A1 297/4885TP53 2618/4885CYP3A4 4794/4885
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 ALDH1A1 113/4885TP53 1767/4885CYP3A4 454/4885
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 ALDH1A1 84/4885TP53 1611/4885CYP3A4 339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.