SCHEMBL5223031

SCHEMBL5223031

CCC(CO)(CO)CO.O=C(O)CCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.34
PSMB5 P28074 1/20 0.34
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2589620 0.91 PSMB8 (0.34) PSMB8PSMB5KDM6BKDM5CEGLN1
Propionic Acid SCHEMBL29510501 0.85 EGLN1 (0.36) PSMB8PSMB5KDM6BKDM5CEGLN1
SCHEMBL43575 0.84 EGLN1 (0.36) PSMB8PSMB5KDM6BKDM5CEGLN1
SCHEMBL5223027 0.84 PSMB8 (0.31) PSMB8PSMB5
Ethylene Glycol SCHEMBL2467342 0.83 PSMB8 (0.35) PSMB8PSMB5KDM6BKDM5CEGLN1
Methoxymethane SCHEMBL7956362 0.83 EGLN1 (0.37) PSMB8PSMB5KDM6BKDM5CEGLN1
SCHEMBL2593469 0.82 TSHR (0.37) PSMB8PSMB5
Urea SCHEMBL4909809 0.79 PSMB8 (0.34) PSMB8PSMB5KDM6BKDM5CEGLN1
Sulfuric Acid SCHEMBL12813397 0.79 PARL (0.35) PSMB8PSMB5KDM6BKDM5CEGLN1
Butyric Acid SCHEMBL28354890 0.79 FFAR3 (0.45) PSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101056595-B Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2012-02-08 CN claimed
CN-101056595-A Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION INC (US) 2007-10-17 CN claimed
EP-1824414-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MicroVention, Inc. (US) 2007-08-29 EP claimed
US-7201918-B2 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2007-04-10 US claimed
WO-2006055690-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MICROVENTION, INC. (US) 2006-05-26 WO claimed
US-20060105014-A1 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2006-05-18 US claimed
CN-101056595-B Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2012-02-08 CN disclosed
CN-101056595-A Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION INC (US) 2007-10-17 CN disclosed
EP-1824414-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MicroVention, Inc. (US) 2007-08-29 EP disclosed
US-7201918-B2 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2007-04-10 US disclosed
WO-2006055690-A2 COMPOSITIONS, SYSTEMS AND METHODS FOR TREATMENT OF DEFECTS IN BLOOD VESSELS MICROVENTION, INC. (US) 2006-05-26 WO disclosed
US-20060105014-A1 Compositions, systems and methods for treatment of defects in blood vessels MICROVENTION, INC. (US) 2006-05-18 US disclosed