Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221810 | 0.90 | ALDH1A1 (0.46) | L3MBTL1NPC1RAB9AACACAALDH1A1 | |
| SCHEMBL5225894 | 0.76 | DYRK1A (0.44) | L3MBTL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5222944 | 0.74 | ALDH1A1 (0.40) | L3MBTL1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL5225080 | 0.73 | NPSR1 (0.50) | L3MBTL1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5227509 | 0.72 | MAPT (0.55) | L3MBTL1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3945127 | 0.71 | PDE4A (0.61) | L3MBTL1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL5227004 | 0.69 | NPC1 (0.62) | L3MBTL1NPC1RAB9AACACAALDH1A1 | |
| SCHEMBL6985387 | 0.68 | SQOR (0.39) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL5222047 | 0.68 | SYK (0.42) | L3MBTL1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL5221958 | 0.67 | ALDH1A1 (0.51) | L3MBTL1NPC1RAB9AACACAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845089-A1 | Novel lactams and uses thereof | AstraZeneca AB (SE) | 2007-10-17 | — | — | EP | claimed |
| EP-1300399-B1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2007-08-22 | — | — | EP | disclosed |
| US-6664256-B1 | Interleukin- 1 beta inhibitors | KOWA CO., LTD. (JP) | 2003-12-16 | — | — | US | disclosed |
| EP-1300399-A1 | PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |