SCHEMBL5225488

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4298330	0.83	SPR (0.45)	SPRPPARGLMNAMAPT
	SCHEMBL14432776	0.82	TP53 (0.47)	TP53HPGDIRAK4LMNACYP1A2
	SCHEMBL14433142	0.80	ALDH1A1 (0.47)	TP53SPRPPARGLMNACYP1A2
	SCHEMBL14432801	0.79	CYP1A2 (0.41)	TP53LMNACYP1A2MAPTSTAT3
	SCHEMBL6233245	0.79	SPR (0.40)	TP53SPRPPARGIRAK4LMNA
	SCHEMBL5229557	0.78	HPGD (0.46)	TP53HPGDLMNACYP1A2MAPT
	SCHEMBL14432861	0.76	TP53 (0.43)	TP53SPRIRAK4LMNACYP1A2
	SCHEMBL14432873	0.76	PPARG (0.41)	TP53PPARGHPGDLMNACYP1A2
	SCHEMBL14432488	0.76	NAMPT (0.40)	HPGDIRAK4CYP1A2JAK2MAPT
	SCHEMBL14432816	0.76	KDM4E (0.50)	TP53HPGDLMNAPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.