Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229345 | 0.88 | EGFR (0.34) | DRD4DRD3TSHRALDH1A1KDM4E | |
| SCHEMBL5222928 | 0.88 | SMO (0.38) | DRD4DRD3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5226173 | 0.88 | SMO (0.38) | DRD4DRD3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5226844 | 0.86 | SIGMAR1 (0.34) | DRD4DRD3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5226450 | 0.85 | F10 (0.35) | ALDH1A1KMT2A | |
| SCHEMBL5225471 | 0.83 | HRH3 (0.35) | DRD4DRD3KDM4EHRH3DRD2 | |
| SCHEMBL2761177 | 0.82 | DRD4 (0.42) | DRD4DRD3TSHRTRPV6ALDH1A1 | |
| SCHEMBL5226663 | 0.81 | KMT2A (0.44) | DRD4DRD3TSHRTRPV6ALDH1A1 | |
| SCHEMBL5230408 | 0.81 | SLC2A1 (0.32) | TSHRALDH1A1SMN1; SMN2L3MBTL1HCRTR1 | |
| SCHEMBL5226484 | 0.80 | SMO (0.45) | DRD4DRD3TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |