Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230408 | 0.90 | SLC2A1 (0.32) | L3MBTL1SMN1; SMN2HCRTR1MAPTALDH1A1 | |
| SCHEMBL5226173 | 0.90 | SMO (0.38) | SMODRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL5222928 | 0.90 | SMO (0.38) | SMODRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL5229345 | 0.88 | EGFR (0.34) | SMODRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL5226667 | 0.86 | DRD4 (0.39) | SMODRD2DRD4DRD3L3MBTL1 | |
| SCHEMBL5226450 | 0.85 | F10 (0.35) | ALDH1A1KMT2A | |
| SCHEMBL5229304 | 0.82 | ALDH1A1 (0.33) | SMN1; SMN2MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL5225471 | 0.82 | HRH3 (0.35) | SMODRD2DRD4DRD3KDM4E | |
| SCHEMBL5224860 | 0.81 | ALDH1A1 (0.31) | MAPTALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL5226838 | 0.80 | ALDH1A1 (0.41) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |