Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | SNCA | P37840 | 3/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024372 | 0.95 | MAOB (0.50) | MAOBMAOASNCANOX1HTT | |
| SCHEMBL21585948 | 0.87 | MAOB (0.57) | MAOBMAOASNCANOX1HTT | |
| SCHEMBL21585923 | 0.78 | KMT2A (0.32) | KMT2A | |
| SCHEMBL22286608 | 0.78 | LMNA (0.35) | LMNAGAAMAPTKMT2AL3MBTL1 | |
| SCHEMBL6843532 | 0.76 | GHSR (0.36) | HTTMEN1MAPTKMT2AMMP13 | |
| SCHEMBL21585955 | 0.74 | LMNA (0.34) | LMNAMAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8031445 | 0.74 | PTPN1 (0.38) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL21586026 | 0.74 | SLC10A2 (0.31) | KMT2A | |
| SCHEMBL23454558 | 0.72 | MAOB (0.51) | MAOBMAOASNCANOX1HTT | |
| SCHEMBL8014423 | 0.72 | SLC6A2 (0.43) | LMNAGAAMAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210977-B1 | NOVEL AMINOALKYL BENZOTHIAZEPINE DERIVATIVE AND USE THEREOF | CJ HEALTHCARE CORP (KR) | 2019-03-20 | — | — | EP | disclosed |
| US-9890129-B2 | Aminoalkylbenzothiazepine derivatives and uses thereof | CJ HEALTHCARE CORPORATION (KR) | 2018-02-13 | — | — | US | disclosed |
| US-20170283386-A1 | NOVEL AMINOALKYLBENZOTHIAZEPINE DERIVATIVES AND USES THEREOF | CJ HEALTHCARE CORPORATION (KR) | 2017-10-05 | — | — | US | disclosed |
| EP-3210977-A2 | NOVEL AMINOALKYL BENZOTHIAZEPINE DERIVATIVE AND USE THEREOF | CJ Healthcare Corporation (KR) | 2017-08-30 | — | — | EP | disclosed |
| EP-1345918-B1 | 1,5 BENZOTHIAZEPINES AND THEIR USE AS ANTIHYPERLIPIDEMICS | ASTRAZENECA AB (SE) | 2007-04-18 | — | — | EP | disclosed |
| US-7192945-B2 | Benzothiazepine derivatives | ASTRAZENECA AB (SE) | 2007-03-20 | — | — | US | disclosed |
| US-20040067933-A1 | Chemical compounds | ELOBIX AB (SE) | 2004-04-08 | — | — | US | disclosed |
| EP-1345918-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067933-A1 | Chemical compounds | SLC10A2, SLC10A1, ABCB11 | MAOB 1297/4885MAOA 2293/4885SNCA 4757/4885 |
| US-20170283386-A1 | NOVEL AMINOALKYLBENZOTHIAZEPINE DERIVATIVES AND USES THEREOF | SLC10A2, TMPRSS15, HTR5A | MAOB 582/4885MAOA 999/4885SNCA 1143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.