Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230062 | 0.72 | LMNA (0.42) | LMNAALDH1A1MAPTHCAR3RAB9A | |
| SCHEMBL5230153 | 0.72 | LMNA (0.51) | LMNAALDH1A1MAPTHCAR3RAB9A | |
| SCHEMBL27328121 | 0.70 | TDP1 (0.38) | ALDH1A1MAPTRAB9AKMT2AGAA | |
| SCHEMBL9498140 | 0.69 | ALDH1A1 (0.65) | LMNAALDH1A1MAPTHCAR3RAB9A | |
| SCHEMBL30568957 | 0.68 | LMNA (0.52) | LMNAALDH1A1MAPTHCAR3RAB9A | |
| SCHEMBL8097857 | 0.68 | LMNA (0.52) | LMNAALDH1A1MAPTHCAR3RAB9A | |
| Hydrochloric Acid SCHEMBL28301069 | 0.65 | GPR35 (0.37) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL11846149 | 0.65 | HCAR3 (0.58) | LMNAALDH1A1MAPTHCAR3RAB9A | |
| SCHEMBL31700569 | 0.65 | LMNA (0.52) | LMNAALDH1A1MAPTHCAR3RAB9A | |
| SCHEMBL2498853 | 0.65 | ALDH1A1 (0.53) | LMNAALDH1A1MAPTHCAR3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |