Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | GLI1 | P08151 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 6/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523144 | 0.98 | NOS2 (0.41) | NOS2NOS3NOS1PRCPSCN4A | |
| SCHEMBL8062198 | 0.79 | NOS2 (0.46) | NOS2NOS3NOS1PRCPGLI1 | |
| Proline SCHEMBL8428394 | 0.74 | NOS2 (0.47) | NOS2NOS3NOS1PRCPGLI1 | |
| Palmitamide SCHEMBL2983849 | 0.73 | PRCP (0.55) | NOS2NOS3NOS1PRCPDPP7 | |
| Palmitamide SCHEMBL2983852 | 0.73 | PRCP (0.55) | NOS2NOS3NOS1PRCPDPP7 | |
| Succinamide SCHEMBL9700026 | 0.72 | NOS2 (0.48) | NOS2NOS3NOS1PRCPGLI1 | |
| SCHEMBL7432758 | 0.72 | NOS2 (0.48) | NOS2NOS3NOS1PRCPSCN4A | |
| SCHEMBL523066 | 0.71 | NOS2 (0.38) | NOS2NOS3NOS1PRCPGLI1 | |
| SCHEMBL6156985 | 0.70 | NOS2 (0.40) | NOS2NOS3NOS1PRCPSCN4A | |
| SCHEMBL30851509 | 0.69 | NOS2 (0.39) | NOS2NOS3NOS1PRCPSCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120027859-A1 | Biodegradable Proline-Based Polymers | MEDIVAS, LLC | 2012-02-02 | — | — | US | disclosed |
| EP-2334343-A1 | BIODEGRADABLE PROLINE-BASED POLYMERS | Medivas, LLC (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010045241-A1 | BIODEGRADABLE PROLINE-BASED POLYMERS | MEDIVAS, LLC (US) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027859-A1 | Biodegradable Proline-Based Polymers | EPRS1, PRAP1, NPEPPS | NOS2 111/4885NOS3 152/4885NOS1 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.