Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | CCKAR | P32238 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238376 | 0.87 | MAPT (0.54) | MEN1KMT2AMAPTALOX15MAPK1 | |
| SCHEMBL5234854 | 0.86 | RAB9A (0.54) | CCKARMEN1NPC1RAB9AKMT2A | |
| SCHEMBL5233951 | 0.82 | MAPT (0.47) | RXRARXRBMGLLCCKARMEN1 | |
| SCHEMBL5460071 | 0.81 | KMT2A (0.59) | MEN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL5239356 | 0.78 | MEN1 (0.68) | MEN1KMT2AMAPTNPSR1TSHR | |
| SCHEMBL3773820 | 0.78 | ACHE (0.47) | RXRARXRBCCKARMEN1NPC1 | |
| SCHEMBL5237744 | 0.77 | RXRA (0.47) | RXRARXRBMGLLCCKARMEN1 | |
| SCHEMBL5236868 | 0.76 | RXRA (0.56) | RXRARXRBMEN1KMT2AMAPK1 | |
| SCHEMBL24629109 | 0.76 | RXRA (0.50) | RXRARXRBMGLLMEN1NPC1 | |
| SCHEMBL5237752 | 0.75 | RXRA (0.44) | RXRARXRBMGLLCCKARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |