Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230479 | 0.78 | LTA4H (0.57) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL22638141 | 0.77 | KIT (0.57) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL5232683 | 0.76 | CHRNB2 (0.46) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL5237792 | 0.75 | GRM5 (0.50) | SIGMAR1HRH3FFAR4HTR1ASLC6A4 | |
| SCHEMBL5237023 | 0.75 | CHRNB2 (0.54) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL8303133 | 0.75 | HTR3E (0.47) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL10305090 | 0.74 | ADRB1 (0.46) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL13344705 | 0.73 | ADRB1 (0.53) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| Hydrochloric Acid SCHEMBL3108154 | 0.73 | ADRB1 (0.45) | SIGMAR1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL3066756 | 0.73 | ADRB1 (0.83) | SIGMAR1HTR3EHTR3BADRB1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |