Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 8/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.46 |
| ▸ | HTR3B | O95264 | 3/20 | 0.46 |
| ▸ | HTR3A | P46098 | 3/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3108154 | 0.98 | ADRB1 (0.45) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL13344705 | 0.83 | ADRB1 (0.53) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24240107 | 0.81 | CHKA (0.49) | NCF1DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL3114267 | 0.78 | ADRB1 (0.53) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4431363 | 0.78 | DRD4 (0.41) | DRD2DRD4DRD3ALDH1A1TSHR | |
| SCHEMBL3117428 | 0.78 | ADRB1 (0.57) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8858015 | 0.77 | ADRB1 (0.61) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3122680 | 0.77 | GRM5 (0.53) | ALDH1A1KDM4ELMNA | |
| SCHEMBL16216149 | 0.76 | GRM5 (0.43) | DRD2DRD4DRD3ALDH1A1KDM4E | |
| SCHEMBL3110614 | 0.76 | CHIA (0.52) | DRD2DRD4DRD3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241509-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-10010631-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-10010631-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20140030189-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2014-01-30 | — | — | US | disclosed |
| US-20140030189-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2014-01-30 | — | — | US | disclosed |
| US-8491868-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| US-8491868-B2 | Ligands for imaging cardiac innervation | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| EP-2114873-B1 | N-[3-BROMO-4-(3- [18F]FLUOROPROPOXY)-BENZYL]-GUANIDINE FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING INC (US) | 2013-02-20 | — | — | EP | disclosed |
| EP-2474524-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474526-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474523-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-2474525-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2010-09-02 | — | — | US | disclosed |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | CITIZENS BANK, N.A. | 2010-09-02 | — | — | US | disclosed |
| WO-2008083056-A2 | LIGANDS FOR IMAGING CARDIAC INNERVATION | LANTHEUS MEDICAL IMAGING, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010631-B2 | Ligands for imaging cardiac innervation | TNNT2, PNMT, TNNC1 | ADRB1 7/4885HTR3E 379/4885HTR3B 250/4885 |
| US-20100221182-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | ADRB1 7/4885HTR3E 379/4885HTR3B 250/4885 |
| US-11241509-B2 | Ligands for imaging cardiac innervation | TNNT2, PNMT, TNNC1 | ADRB1 7/4885HTR3E 332/4885HTR3B 239/4885 |
| US-20140030189-A1 | LIGANDS FOR IMAGING CARDIAC INNERVATION | TNNT2, PNMT, TNNC1 | ADRB1 7/4885HTR3E 379/4885HTR3B 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.