Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234101 | 0.91 | GAA (0.39) | GAAALDH1A1OPRM1CACNA2D1USP2 | |
| SCHEMBL5237036 | 0.91 | CACNA2D1 (0.42) | ALDH1A1OPRM1CACNA2D1CHRM2CHRM3 | |
| SCHEMBL5237215 | 0.89 | CACNA2D1 (0.36) | ALDH1A1OPRM1CACNA2D1UCHL1CHRM2 | |
| SCHEMBL5233869 | 0.88 | OPRM1 (0.36) | GAAOPRM1CACNA2D1CHRM2CHRM3 | |
| SCHEMBL5238148 | 0.87 | POLB (0.40) | ALDH1A1L3MBTL1OPRM1CACNA2D1NPY5R | |
| SCHEMBL5237690 | 0.87 | CACNA2D1 (0.41) | OPRM1CACNA2D1UCHL1 | |
| SCHEMBL5235781 | 0.87 | ALDH1A1 (0.34) | GAAALDH1A1L3MBTL1OPRM1CACNA2D1 | |
| SCHEMBL5235207 | 0.87 | L3MBTL1 (0.35) | ALDH1A1L3MBTL1OPRM1CACNA2D1NPY5R | |
| SCHEMBL5235195 | 0.87 | L3MBTL1 (0.35) | ALDH1A1L3MBTL1OPRM1CACNA2D1NPY5R | |
| SCHEMBL5232225 | 0.83 | NPSR1 (0.43) | ALDH1A1L3MBTL1OPRM1CACNA2D1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730116-B1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2007-09-05 | — | — | EP | claimed |