Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281277 | 0.87 | LOXL2 (0.44) | LOXL2MAOA | |
| SCHEMBL5236219 | 0.75 | MAOA (0.64) | MAOAIKBKBACHEMAOBNUDT1 | |
| SCHEMBL11096994 | 0.72 | SRD5A1 (0.49) | MAOAPOLBMAOBMAPT | |
| SCHEMBL10689679 | 0.71 | HTR1A (0.48) | PTPN1CDK1CCNB1MAPT | |
| SCHEMBL5349187 | 0.70 | MAOA (0.76) | MAOAACHEPOLBMAOBABCB1 | |
| SCHEMBL5239013 | 0.69 | LOXL2 (0.47) | LOXL2MAOAMAPT | |
| SCHEMBL4238441 | 0.68 | CYP2C19 (0.42) | MAOBRELAPTPN1CDK1CCNB1 | |
| SCHEMBL7172523 | 0.67 | HTR1A (0.46) | BCHEABCB1MAPT | |
| SCHEMBL7561778 | 0.67 | CYP2C19 (0.41) | RELAPTPN1MAPT | |
| SCHEMBL7546749 | 0.66 | BCHE (0.60) | MAOABCHEACHEMAOBABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585740-A4 | PROCESS TO PREPARE PSOROSPERMIN | CYLENE PHARMACEUTICALS INC (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1585740-A2 | PROCESS TO PREPARE PSOROSPERMIN | Cylene Pharmaceuticals, Inc. (US) | 2005-10-19 | — | — | EP | disclosed |
| US-6933396-B2 | Process to prepare psorospermin | CYLENE PHARMACEUTICALS (US) | 2005-08-23 | — | — | US | disclosed |
| US-20040102515-A1 | Process to prepare psorospermin | CYLENE PHARMACEUTICALS | 2004-05-27 | — | — | US | disclosed |
| WO-2004019888-A2 | PROCESS TO PREPARE PSOROSPERMIN | CYLENE PHARMACEUTICALS, INC. (US) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102515-A1 | Process to prepare psorospermin | BPGM, DHPS, FDPS | LOXL2 3973/4885MAOA 761/4885IKBKB 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.