Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | PDE4A | P27815 | 3/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272670 | 0.92 | PDE4A (0.65) | ADORA2BLMNAPDE4APDE4BPDE4C | |
| SCHEMBL5275531 | 0.91 | PDE4A (0.60) | ADORA2BLMNAPDE4APDE4BPDE4C | |
| Etofylline SCHEMBL149271 | 0.84 | ADORA2B (1.00) | ADORA2BLMNAPDE4APDE4BPDE4C | |
| SCHEMBL28752095 | 0.81 | ALDH1A1 (0.75) | ADORA2BLMNASMN1; SMN2POLBRXFP1 | |
| SCHEMBL556077 | 0.79 | SMN1; SMN2 (0.74) | ADORA2BLMNASMN1; SMN2POLBMAPK1 | |
| SCHEMBL11366248 | 0.77 | PDE4A (0.58) | ADORA2BLMNAPDE4APDE4BPDE4C | |
| SCHEMBL9293406 | 0.75 | ADORA2B (0.83) | ADORA2BLMNAPDE4APDE4BPDE4C | |
| SCHEMBL20011104 | 0.74 | LMNA (0.62) | ADORA2BLMNASMN1; SMN2POLBMAPT | |
| SCHEMBL8697228 | 0.74 | ADORA2B (0.81) | ADORA2BLMNAPDE4APDE4BPDE4C | |
| SCHEMBL11359942 | 0.74 | RXFP1 (0.67) | ADORA2BLMNAPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829523-A1 | Cosmetic use of an N-oxide derivative of theophylline | L'OREAL (FR) | 2007-09-05 | — | — | EP | disclosed |