Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233508 | 0.86 | CNR2 (0.53) | CNR2CYP1A2TLR7KDRBRAF | |
| SCHEMBL5237313 | 0.85 | RAB9A (0.56) | CYP1A2MEN1KMT2APTPN1LOXL2 | |
| SCHEMBL5239658 | 0.84 | CYP1A2 (0.61) | CYP1A2MEN1KMT2APTPN1LOXL2 | |
| SCHEMBL29987166 | 0.84 | CYP1A2 (0.61) | CYP1A2MEN1KMT2APTPN1LOXL2 | |
| SCHEMBL5235487 | 0.84 | CYP1A2 (0.44) | CNR2CYP1A2LOXL2TACR1KDR | |
| SCHEMBL5233678 | 0.82 | RAB9A (0.56) | CYP1A2MEN1KMT2ALOXL2KDM4E | |
| SCHEMBL5239743 | 0.81 | VNN1 (0.44) | CYP1A2LOXL2KDR | |
| SCHEMBL5237502 | 0.81 | LOXL2 (0.43) | CNR2CYP1A2BCHELOXL2PTGDR2 | |
| SCHEMBL5235015 | 0.81 | LOXL2 (0.43) | CNR2CYP1A2BCHELOXL2PTGDR2 | |
| SCHEMBL17583692 | 0.79 | TDP1 (0.53) | CNR2MEN1KMT2APTPN1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397364-B1 | NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | LILLY CO ELI (US) | 2007-07-25 | — | — | EP | disclosed |