Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237607 | 0.86 | KDM4E (0.47) | L3MBTL1LMNAMAPTGAAKDM4E | |
| SCHEMBL5239244 | 0.85 | ALDH1A1 (0.52) | L3MBTL1LMNAMAPTGAAKDM4E | |
| SCHEMBL5445795 | 0.83 | KDM4E (0.42) | CD274L3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL5238406 | 0.83 | L3MBTL1 (0.51) | L3MBTL1MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL5236980 | 0.82 | L3MBTL1 (0.50) | L3MBTL1LMNAMAPTGAAKDM4E | |
| SCHEMBL5233485 | 0.82 | NPSR1 (0.50) | L3MBTL1LMNAMAPTGAAALDH1A1 | |
| SCHEMBL5233312 | 0.82 | FGFR1 (0.47) | L3MBTL1LMNAMAPTGAAKDM4E | |
| SCHEMBL5233512 | 0.81 | MAPT (0.51) | L3MBTL1LMNAMAPTGAAKDM4E | |
| SCHEMBL5233900 | 0.81 | ALDH1A1 (0.55) | L3MBTL1LMNAMAPTGAAKDM4E | |
| SCHEMBL5236702 | 0.80 | FAAH (0.57) | L3MBTL1LMNAMAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |