Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 6/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235446 | 0.89 | ALDH1A1 (0.37) | MEN1KMT2AHTTMAPTHSD17B10 | |
| SCHEMBL5239098 | 0.88 | MEN1 (0.39) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL5231079 | 0.87 | DGAT1 (0.39) | MARS1MCHR1CNR1EPHX2 | |
| SCHEMBL5236743 | 0.83 | ALDH1A1 (0.45) | RAB9AMEN1KMT2AHTTNPSR1 | |
| SCHEMBL5235809 | 0.83 | MAPT (0.44) | RAB9AMEN1KMT2AHTTNPSR1 | |
| SCHEMBL5237009 | 0.83 | DGAT1 (0.39) | MARS1MCHR1CNR1EPHX2 | |
| SCHEMBL5236555 | 0.83 | USP2 (0.41) | MEN1KMT2AMAPTTSHRHSD17B10 | |
| SCHEMBL5236419 | 0.82 | ADAMTS5 (0.39) | KMT2AMAPT | |
| SCHEMBL5232377 | 0.81 | SMN1; SMN2 (0.37) | RAB9AMEN1KMT2AATMHTT | |
| SCHEMBL5234847 | 0.81 | KMT2A (0.40) | RAB9AMEN1KMT2AMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |